Myocardial Ischemia & infarction: Reactions, ECG Changes & Symptoms
Myocardial ischemia: reactions, ECG and development of infarction As all other cells in the human body, cardiac myocytes use ATP (adenosine triphosphate) as the primary energy source. ATP is produced by metabolizing carbohydrates (glucose), fats or proteins, whichever is available. ATP fuels all cellular functions, such as contraction and relaxation. Increasing cardiac workload by increasing heart rate and contractility (i.e contractile force), results in increased metabolism. Cardiac cells are highly capable of matching the supply and demand of ATP; increased cardiac workload results in increased ATP production and vice versa . Importantly, cardiac myocytes require aerobic metabolism (oxygen) to produce sufficient quantities of ATP. This implies that the heart require continuous blood flow to maintain cellular function. Myocardial ischemia occurs when there is insufficient oxygen available. Insufficient oxygen supply results in diminished ATP production and subsequently disruption of ce…
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Cuộc đời thì ngắn, mà nghề thì miên man;cơn bệnh phập phù;kinh nghiệm hiểm nguy, còn quyết định thì thật khó.Người thầy thuốc không phải chỉ chuẩn bị để tự mình làm đúng, mà còn khiến cho bệnh nhân, người đi theo và các yếu tố xung quanh hợp tác hài…